RAMI Research Awards 2022_Monday 25th September 2023

25/09/2023 in RCSI, 123, St Stephen Green, Dublin 2

The Royal Academy of Medicine in Ireland in association with the Irish Journal of Medical Science hosted the RAMI Research Awards 2022.  The event was held at the Royal College of Surgeons in Ireland.  

The three (3) shortlisted papers and winning papers in each category are as follows:

Biomedical Science

• Proteomics profiling identifies extracellular vesicles’ cargo associated with tumour cell induced platelet aggregation (Niamh McNamee, Laura Rodriguez de la Fuente, Maria Jose Santos-Martinez, Lorraine O’Driscoll)
• Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities (Nicola Cosgrove, Damir Vareslija, Stephen Keelan, Ashuvinee Elangovan, Jennifer M Atkinson, Sinead Cocchiglia, Fiona T Bane, Vikrant Singh, Simon Furney, Chunling Hu, Jodi M Carter, Steven N Hart, Siddharta Yadav, Matthew P Goetz, Arnold DK Hill, Steffi Oesterreich, Adrian V Lee, Fergus J Couch, Leonie S Young)
• Impact of Fluid Flow Shear Stress on Osteoblast Differentiation and Cross-Talk with Articular Chondrocytes (Paige V Hinton, Katelyn J. Genoud, James O. Early, Fergal J. O’Brien, Oran D. Kennedy)

Prof. James Jones presented a medal to Dr Damir Vareslija for the winning paper in the Biomedical Science category, “Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities”.

Endocrinology

• Parent and Child Perceptions of Physical Activity with Type 1 (Susan Giblin, Paul Scully, Niall Dalton, Alison McCaffrey, Muiriosa Connolly, Clodagh O’Gorman)
• Diabetes Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma (Kate M Warde, Yi Jan Lim, Eduardo Ribes Martinez, Felix Beuschlein, Paula O’Shea , Constanze Hantel , Michael Conall Dennedy)
• Re interpreting growth hormone response to hypoglycaemia (U A Khan, F Y Wong, S Azam, O Blake, A M Murphy, O M Neylon, C S O’Gorman)

The medal was awarded to Dr Kate M. Warde for the winning paper in the Endocrinology category, “Diabetes Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma”.

Public Health Medicine/ Epidemiology

• Screen-detected ductal carcinoma in situ 2008-2020 An observational study (Caitriona Kelly, Patricia Fitzpatrick, Cecily Quinn, Fidelma Flanagan, Alissa Connors, Aideen Larke, Therese Mooney, Maria Kennedy, Margaret Sheehan, Michael W Bennett, Caroline Brodie, Ann O’Doherty)
• Clinical efficacy and effectiveness of alternative varicella vaccination strategies – an overview of reviews (Susan Ahern, Kieran A Walsh, Simona Paone, John Browne, Marie Carrigan, Patricia Harrington, Aileen Murphy, Conor Teljeur, Mairin Ryan)
• Cost effectiveness of metabolic surgery for the treatment of type 2 diabetes and obesity A systematic review of economic evaluations (Karen Jordan, Christopher G. Fawsitt, Paul G. Carty, Barbara Clyne, Conor Teljeur, Patricia Harrington, Mairin Ryan)

The medal was presented by Prof. James Jones to Dr Caitriona Kelly for the winning paper in the Public Health Medicine/epidemiology category, “Screen-detected ductal carcinoma in situ 2008-2020 An observational study”.

General Practice

• Can a practice pharmacist improve prescribing safety and reduce costs in polypharmacy patients- A pilot study of an intervention in an Irish general practice setting (Darach Ó Ciardha, Anne-Marie Blake, Dylan Creane, Michael Ó Callaghan, Catherine Darker)
• Anticipatory care planning for community dwelling older adults at risk of functional decline – a feasibility cluster randomized controlled trial (Kevin Brazil, Christopher Cardwell, Gillian Carter, Mike Clarke, Dagmar Anna S. Corry, Tom Fahey, Patrick Gillespie, Anna Hobbins, Kieran McGlade, Peter O’Halloran, Nina O’Neill, Emma Wallace, Frank Doyle)
• The evaluation of a training course to enhance intellectual disabilities and mental health awareness amongst General Practitioners attending police stations (Gautam Gulati, Valerie Murphy, Gurjot Brar, Shane Kilcommins, Alan Cusack, Colum Dunne, Liam Glynn, Brendan Kelly)

Prof. Jones presented a medal to Professor Valerie Murphy for the winning paper in the General Practice category, “The evaluation of a training course to enhance intellectual disabilities and mental health awareness amongst General Practitioners attending police stations”.

Medical Microbiology

• Association between tocilizumab treatment of hyperinflammatory patients with COVID-19 in a critical care setting and elevated incidence of hospital-acquired bacterial and invasive fungal infections (B Minihan, E McAuliffe, J Powell, S L Wong, K Wilkie, C Murphy, A Maher, L Power, N H O’Connell, C P Dunne)
• Repeated transmission of SARS-CoV-2 in an overcrowded Irish emergency department elucidated by whole-genome sequencing (D Hare, C Meaney, J Powell, B Slevin, B O’ Brien, L Power, N H O’ Connell, C F De Gascun, C P Dunne, P J Stapleton)
• Outcomes of implementation of the FilmArray meningoencephalitis panel in a tertiary hospital between 2017 and 2020 (TeeKeat Teoh, James Powell, Jillian O’Keeffe, Eoghan Donlon, Lisa Dillon, Marie Lenihan, Amanda Mostyn, Lorraine Power, Peter Boers, Patrick J Stapleton, Nuala H O’Connell, Colum P Dunne)

Prof. James Jones presented the winner Dr Daniel Hare with a medal for the winning paper in the Medical Microbiology category, “Repeated transmission of SARS-CoV-2 in an overcrowded Irish emergency department elucidated by whole-genome sequencing”.

Oncology

• Diagnostic Accuracy of Blood-based Biomarkers for Pancreatic Cancer A Systematic Review and Meta-analysis (Laura E. Kane, Gregory S. Mellotte, Eimear Mylod, Rebecca M. OBrien, Fiona O’Connell, Croí E. Buckley, Jennifer Arlow, Khanh Nguyen, David Mockler, Aidan D. Meade, Barbara M. Ryan and G. Stephen Maher)
• Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy (K White, K Connor, M Meylan, A Bougoüin, M Salvucci, F Bielle, A C O’Farrell, K Sweeney, L Weng, G Bergers, P Dicker, D M Ashley, E S Lipp, J T Low, J Zhao, P Wen, R Prins, M Verreault, A Idbaih, A Biswas, J H M Prehn, D Lambrechts, I Arijs, F Lodi, G Dilcan, M Lamfers, S Leenstra, F Fabro, I Ntafoulis, J M Kros, J Cryan, F Brett, E Quissac, A Beausang, S MacNally, P O’Halloran, J Clerkin, O Bacon, A Kremer, R T Chi Yen, F S Varn, R G W Verhaak, C Sautès-Fridman, W H Fridman, A T Byrne)
• Sources of nutrition advice and desired nutrition guidance in oncology care- Patient’s perspectives (Laura Keaver, Janice Richmond, Fiona Rafferty, Pauline Douglas)

Prof.  James Jones presented a medal to Dr Kieron White, who accepted on behalf of Dr Annette T. Byrne for the winning paper in the Oncology category, “Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy”.

Ophthalmology

• Electrophysiology-Guided Genetic Characterisation Maximises Molecular Diagnosis in an Irish Paediatric Inherited Retinal Degeneration Population (Kirk A. J. Stephenson, Julia Zhu, Adrian Dockery, Jacqueline Turner, James J. O’Byrne, Susan Fitzsimon, G. Jane Farrar, D. Ian Flitcroft, David J. Keegan)
• Electrophysiology-Guided Genetic Characterisation Maximises Molecular Diagnosis in an Irish Paediatric Inherited Retinal Degeneration Population (Julia Zhu, Kirk Stephenson, Adrian Dockery, Jacqueline Turner, James J. O’Byrne, Susan Fitzsimon, Jane Farrar, Ian Flitcroft, David Keegan)
• Neuromyelitis optica spectrum disorders and anti-myelin oligodendrocyte glycoprotein positive optic neuropathies (Patrick Murtagh, Amy Coman, Kirk Stephenson, Maria Gaughan, David Ryan, Graeme McNeill, Christopher McGuigan , Lorraine Cassidy)

Prof. James Jones presented the medal to Dr Julia Zhu, for the winning paper in the Ophthalmology category, “Electrophysiology-Guided Genetic Characterisation Maximises Molecular Diagnosis in an Irish Paediatric Inherited Retinal Degeneration Population“.

The Ophthalmology category was kindly sponsored by Santen.  The event was attended by their representative Mr. Declan Daly, accompanied by Mr. Neil Goode.

Psychiatry

• Neuroanatomical markers of psychotic experiences in adolescents A machine-learning approach in a longitudinal population-based sample (Joanne Kenney, Laura Milena Rueda Delgado, Erik O Hanlon, Lee Jollans, Ian Kelleher, Colm Healy, Niamh Dooley, Conor McCandless, Thomas Frodl, Alexander Leemans, Catherine Label, Robert Whelan, Mary Cannon)
• Person-Centered Trajectories of Psychopathology From Early Childhood to Late Adolescence (Colm Healy, Ross Brannigan, Niamh Dooley, Lorna Staines, Helen Keeley, Robert Whelan, Mary Clarke, Stanley Zammit, Ian Kelleher, Mary Cannon)
• Mentalization-Based Treatment in a Naturalistic Setting in Ireland – A Cohort Study (Kezanne Tong, Sinead Costello, Evelyn McCabe, Anne M Doherty)

Prof. James Jones presented a medal to the winner, Dr Colm Healy for the winning paper in the Psychiatry category, “Person-Centered Trajectories of Psychopathology From Early Childhood to Late Adolescence”.

Click here for the “Photographs of the RAMI Research Awards 2022, held on Monday 25th September 2023“.